Extrusion trials were conducted with varying degrees of distillers dried grains with solubles (DDGS) alongside soy flour, corn flour, fish meal, vitamin mixture, mineral combine, and net protein content adjusted to 28% using a Wenger TX-52 twin-screw extruder. The real estate of extrudates were studied in experiments executed using a full-factorial design with three levels of DDGS content, two levels of moisture content material, and two levels of screw velocity. Raising the DDGS articles from 20 to 60% led to a 36.7% reduction in the radial growth, leading to a 159 and 61.4% upsurge in the machine density and mass density of the extrudates, respectively. Raising the DDGS content resulted in a significant increase in the water absorption index (WAI) but a substantial decrease in the water solubility index (WSI) of the extrudates. Changing the screw double screw extruder speed and moisture content had no significant effect on the radial growth ratio but led to a significant difference in the bulk density of the extrudates, which might be due to the occurrence of longitudinal growth. Despite the fact that changing the moisture screw and content acceleration had no significant influence on the WSI of the extrudates, significant distinctions in the WAI of the extrudates were observed. The ingredient components in the blend and moisture content had an influence on the color changes of the extrudates, as did the biochemical changes occurring inside the barrel during digesting. Overall, it was established that DDGS could possibly be included at a rate as high as 60% employing twin-screw extrusion, and that practical pelleted floating feeds could be produced.