A single-screw laboratory extruder was used to carry out an L18 Taguchi fractional factorial study of aquafeed processing. The elements were based on a formulation for nutritionally-balanced Nile tilapia weight loss plans containing distillers dried grains with solubles and soybean food as the main protein options, furthermore to constant levels of corn flour, whey, and fishmeal. The effects of three degrees of DDGS, soybean meal, ingredient moisture content material, screw rate, die dimension, barrel temperature and two levels of screw configuration on extrudate physical extruder and houses processing parameters were determined. Data from recycleables, processing conditions, and extrudate properties were used to build up surface response curves and equations. However, predominantly low R2 values simply permitted linear relationships around some people independent response and parameters variables. Regarding main effects, die pressure decreased with bigger DDGS levels significantly, moisture content, temperatures, lower die L/D, and higher screw compression. Expansion ratio decreased with higher dampness articles and lower die L/D significantly. Significant differences on color were due to changes on DDGS moisture and levels content material. In summary, DDGS, moisture content, die dimension, and extrusion conditions had the biggest impact on the majority of the extrudate mixer extruder physical homes and processing conditions. Numerous combinations of these independent factors may be used to obtain desired extrudate physical homes and processing conditions.